HLA-DM - Wikipedia, the free encyclopedia HLA-DM (human leukocyte antigen DM) is an intracellular protein involved in peptide presentation by MHC class II. It is encoded by the genes HLA-DMA and ...
CLIP (protein) - Wikipedia, the free encyclopedia In presence of antigen peptide fragments, HLA-DM then binds to the MHC II molecule, releasing CLIP and allowing peptides to bind. MHC II with bound antigen ...
HLA-DMA - Wikipedia, the free encyclopedia Major histocompatibility complex, class II, DM alpha ... HLA class II histocompatibility antigen, DM alpha chain is a protein that in humans is encoded by the ...
Russ McCracken: HLA-DM - Biology Department - Davidson College HLA-DM. Introduction. The ability of the immune system to recognize and defend against the introduction of foreign antigens is partially dependent upon the ...
HLA-DM induces CLIP dissociation from MHC class II alpha beta ... 14 Jul 1995 ... Human leukocyte antigen DM (HLA-DM) molecules are structurally related to classical MHC class II molecules and reside in the lysosome-like ...
Accumulation of HLA-DM, a regulator of antigen presentation, in ... The HLA-DM genes encode an unconventional HLA (human leukocyte antigen) class II molecule that is required for appropriate binding of peptide to classical ...
Mechanisms of peptide repertoire selection by HLA-DM. 5 Jul 2013 ... HLA-DM functions in antigen presentation by catalyzing dissociation of an invariant chain remnant from the peptide binding groove and ...
Mechanisms of peptide repertoire selection by HLA-DM: Trends in ... 9 Jul 2013 ... •HLA-DM stabilizes empty HLA-DR1 through major conformational changes of the groove. •These conformational changes enable a rapid ...
HLA-DM induces clip dissociation from MHC class II αβ dimers and ... Abstract. Human leukocyte antigen DM (HLA-DM) molecules are structurally related to classical MHC class II molecules and reside in the lysosome-like ...
Short peptide sequences mimic HLA-DM functions - Johns Hopkins ... Available online at www.sciencedirect.com. Molecular Immunology 45 (2008) 1935–1943. Short peptide sequences mimic HLA-DM functions. Chih-Ling Chou b ...